CAS: 474-25-9 Pure Chenodeoxycholic Acid Powder 98% Extract From Chicken Bile

• CAS No.: 474-25-9
• Formula: 474-25-9
• EINECS: 474-25-9
• Resource: Natural
• Source: Chicken Bile Extract
• Product Name: Chenodeoxycholic Acid
• Model NO.: Chicken Bile
• Other Product Name: Chicken Bile Powder
• Transport Package: Drum
• Specification: 20-99%
• Trademark: NO
• Origin: China

Product Description

CAS: 474-25-9 Pure Chenodeoxycholic Acid Powder 98% Extract From Chicken Bile

Detailed Photos

Product Description

Product Name:Chenodeoxycholic Acid

CAS:474-25-9
Molecular Formula: C₂₄H₄₀04
Molecular Mass:392.58
[Appearance]: white crystal powder, no foreign substance, no obvious odor
[Melting Point]: 197~202.0ºC
[Loss on Dry]: ≤1.0%
[Residue on Ignition]: ≤0.1%
[Heavy Metal ]: ≤10ppm
[Assay Determination]: 98.0%~101.0% (dries basis)
[Related Substance]:the single impurity≤0.1%, total impurities≤2.0%
[Package and Storage Condition]: 25kg/drum, store and seal away from light
 

What is Chenodeoxycholic acid(CDCA)?
Chenodeoxycholic acid (CDCA; also known as chenodesoxycholic acid, chenocholic acid and 3α,7α-dihydroxy-5β-cholan-24-oic acid) is a bile acid. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids.It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name .
 

Chenodeoxycholic acid is a bile acid. Bile acids are steroid acids found predominantly in the bile of mammals. The distinction between different bile acids is minute, depending only on the presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are also steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis. Bile acids recirculate through the liver, bile ducts, small intestine and portal vein to form an enterohepatic circuit. They exist as anions at physiological pH and, consequently, require a carrier for transport across the membranes of the enterohepatic tissues. The unique detergent properties of bile acids are essential for the digestion and intestinal absorption of hydrophobic nutrients. Bile acids have potent toxic properties (e.g. membrane disruption) and there are a plethora of mechanisms to limit their accumulation in blood and tissues.Usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
 

Product Name	Chenodeoxycholic Acid
Assay	90%;95%;98%
Appearance	White Powder
Shelf life	2 years

 

Functions

Chenodiol suppresses hepatic synthesis of both cholesterol and cholic acid, gradually replacing the latter and its metabolite, deoxycholic acid in an expanded bile acid pool. These actions contribute to biliary cholesterol desaturation and gradual dissolution of radiolucent cholesterol gallstones in the presence of a gall-bladder visualized by oral cholecystography. Bile acids may also bind the the bile acid receptor (FXR) which regulates the synthesis and transport of bile acids.

Chenodeoxycholic acid is a naturally occurring bile acid that is used to treat patients with genetic deficiencies in the synthesis of bile acids. When given in high doses, cholic acid replacement therapy has been linked to minor elevations in serum aminotransferase levels, but it has not been linked to instances of clinically apparent acute liver injury with jaundice.

Payment terms

 

Packaging & Shipping

 

Package	1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
Transit	Fedex, TNT,DHL,EMS,and so on.
Shipping port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	1-2 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

Company Profile

Hefei JOYE Import & Export CO.,LTD is a import and export trade company established in 2011.Approved by the Chinese government set up trade enterprises.The Customs Registration code of the company is 3401961603.

We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!

We adhering to the "pragmatic, serious, responsible, efficient" management thought construction of the unique enterprise culture, and provide the best service and high quality products, and you achieve mutual reciprocity and mutual benefit relations of cooperation.

Any questions or doubts,pls do not hesitate to contact with me!