| Character: | White Powder |
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| Package: | 1kg/Aluminum Foil Bag |
| Test: | HPLC |
| Name: | Lappaconitine Hydrobromide |
| Source: | Wheat Extract |
| Transport Package: | Drum/Tin |
| Samples: |
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| Customization: |
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Audited Supplier Supply Aconitum Extract Lappaconitine Hydrobromide 98%
Chemical Name: LAPPACONITINE HYDROBROMIDE
CAS No.: 97792-45-5
Chemical Structure: C32H45BrN2O8
Molecular weight: 665.61
Appearance: White powder
Assay: 98%min
Lappanonitine Hydrobromide is an alkaloid, which is extracted from the roots of Aconitum sinomontanum Nakai(Ranunculaceae). As a surgical analgesic and an adjuvant drug for radiotherapy and chemotherapy.
Analgesic effect of Lappaconitine Hydrobromide is seven times as strong as aminopyrine, equivalent with dola ntin. Lappaconitine Hydrobromide is made into transdermal preparation with the advantages of convenient administration and non-invasion.
1.Analgesic effect
Hypermorphine hydrobromide can affect the central nervous system voltage-dependent sodium channel to inhibit axonal injury caused by ectopic discharge, play a role in blocking nerve conduction; by inhibiting the presynaptic membrane of norepinephrine and Serotonin re-uptake, so that synaptic clearance increased, thereby inhibiting the release of fiber and somatostatin release and play a strong and lasting analgesic effect; analgesic effects in addition to these mechanisms, but also with the inhibition of brain Water around the gray matter and cortical calcium influx and so on.
2. anti-inflammatory swelling effect
The body damage can induce inflammatory cells to produce a large number of chemokines, triggering the immune response, immune factors, immune factors can stimulate, induce and regulate the inflammatory response, but also activate the neuroendocrine system to produce stress hormones, the body in a stress state. Hyperbarergenic hydrobromide can reduce the inflammatory response of the local tissue of the wound, reduce the formation and absorption of inflammatory mediators, block the stimulation of the neuroendocrine system and mobilize the immune system of the starting factors, indicating that the high eruption It has the effect of inhibiting postoperative stress response and acute and chronic inflammation, and it provides a theoretical basis for its clinical treatment of rheumatism, rheumatoid arthritis caused by swelling and pain.
3. The role of the heart
Hydrogenated hydrobromide is a natural compound with antiarrhythmic effects that can inhibit the depolarization of the heart directly or indirectly by regulating the expression of the voltage dependent sodium / potassium channel and the associated protein gene on the channel; The excitability of the cardiac conduction system exerts its antiarrhythmic effect. Hypermorphine hydrobromide can reduce myocardial contractility by increasing the myocardial excitability by arranging potential-dependent sodium channels, leading to bradycardia or cardiac arrest, in order to exert its antiarrhythmic effects.
4. Other effects
Recent studies have found that, in addition to analgesic, antiarrhythmic and anti-inflammatory swelling has a good role, but also has antiepileptic, anti-tumor, anti-bacterial, anti-oxidation and immune regulation and so on. Hypermorphine hydrobromide can control epilepsy activity by inhibiting hippocampal neuronal activity.
(1) Aconite root extract Powder is applied in the nutraceuticals food, it has become a new raw material which used in food andnutraceuticals industry;
(2) Aconite root extract Powder is applied in the health product field;
(3) Aconite root extract Powder is applied in the pharmaceutical field;
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Package
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1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
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Transit
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Fedex, TNT,DHL,EMS,and so on.
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Shipping port
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Shanghai/Tianjin/Dalian/Beijing/Xi'an
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Lead Time
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1-2 working days upon received the payment
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For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
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Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service:
1)International Authorized Third-Party Test For The Products You Demand.
2)60 Days Warranty of quality of goods.
Hefei JOYE Import & Export CO.,LTD is a import and export trade company established in 2011.Approved by the Chinese government set up trade enterprises.The Customs Registration code of the company is 3401961603.
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