| CAS No.: | 68-19-9 |
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| Formula: | 68-19-9 |
| EINECS: | 68-19-9 |
| Packaging Material: | Metal |
| Storage Method: | Normal |
| Shelf Life: | >12 Months |
| Samples: |
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| Customization: |
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Audited Supplier Factory API Vitamin B12 Cyanocobalamin Powder CAS 68-19-9
Vitamin B12, also known as cobalamin, is the only vitamin containing metallic elements. Vitamin B12 is synthesized by microorganisms in nature. Higher plants and animals cannot produce vitamin B12. Vitamin B12 is the only vitamin that needs the help of an intestinal secretion (endogenous factor) to be absorbed. Some people, due to gastrointestinal abnormalities, lack this endogenous factor, even if the diet is adequately sourced, will suffer from pernicious anemia. There is basically no vitamin B12 in vegetable foods. It stays in the intestine for a long time and takes about three hours (most water-soluble vitamins take only a few seconds) to be absorbed. The main physiological function of vitamin B12 is to participate in the production of bone marrow red blood cells, prevent pernicious anemia, and prevent brain nerve damage. Vitamin B12 is the latest B vitamin found so far. Vitamin B12 is a polycyclic compound containing cobalt trivalent. Four reduced pyrrole rings are linked together to form a macrocyclic compound (similar to porphyrin), which is the core of vitamin B12 molecule. So compounds containing these rings are called guolinoid-like compounds. Vitamin B12 is a light red acicular crystal, soluble in water and ethanol. It is the most stable under the weak acid condition of pH 4.5-5.0. It can be decomposed in strong acid (pH < 2) or alkaline solution. It can be destroyed to a certain extent when heated, but the loss of high temperature disinfection in a short time is small, and it is easy to be destroyed by strong light or ultraviolet rays. The loss of ordinary cooking process is about 30%.
| Items | Specification | Results | Test method |
| Appearance | Dark red crystalline powder or crystals | Complies | JP Monograph Visual method |
Identification |
(1)UV:Compare the spectrum with the reference spectrum,Both spectraexhibit similar intensities of absorption at the same wavelengths | Complies | JP Monograph/JP<2.24> |
| (2)Chemical:meets JP requirements | Complies | JP Monograph | |
| (1)Clarity and color of solution | Solution is clear and red color | Complies | JP Monograph |
(2)Related substances |
Each area of the peaks other than mecobalamin is not larger than 0.5% of the peak area of mecobalamin | Complies | JP Monograph/JP<2.01> |
| The total area of the peaks other than mecobalamin is not larger than 2.0% | 0.88% | JP Monograph/JP<2.01> | |
| Water | ≤11.5% | 5.58% | JP Monograph Visual method/JP<2.48> |
| Assay | ≥98.5% | 100.31% | JP Monograph |
| Residual solvents | Acetone≤0.5% | <0.00025% | In house/(GC) |
| Total Plate count | ≤800cfu/g | <10cfu/g | Ch.P.Appendix XI J |
| Yeast and Molds | ≤80cfu/g | <10cfu/g | |
| E.coli | Negative | Complies |
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Product Name
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Cyanocobalamin(Vitamin B12)
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CAS No.
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68-19-9
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Appearance
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Dark red crystal or crystalline powder
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Purity
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98.0% --101.0%
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Molecular formula
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C63H88CoN14O14P
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Molecular weight
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1355.38
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EINECS
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200-680-0
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Water solubility
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Soluble
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Property description
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Dark red crystal or crystalline powder. It does not dissolve at 300 ºC. It has hygroscopicity, can absorb 12 moisture in air, and its water crystal is stable in air. The color became darker at 210-220 ºC. It is insoluble in and ether. The solution is neutral and the most stable at pH 4.5-5. It can be hydrolyzed slowly in alkaline or strong acid solution, tasteless. The structure of vitamin B12 is complex. Its molecular characteristics include cobalt atom and cyano group. Vitamin B12 exists in liver, egg, milk, fish meal, soybean, yeast and meat. In 1926, G. R. vanott and W. P. Murphy found that liver extract had medical productivity for pernicious anemia, and thus found vitamin B12. |
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1) Vitamin B12 can resistance to fatty liver, promote storage of vitamin A in liver
2) Vitamin B12 Promote cell mature and body metabolism.
3) Vitamin B12 participates in the manufacturing of bone marrow RBC ,so it can be the treatment of pernicious anemia.
4) Vitamin B12 increases folic acid utilization rate, promote carbohydrate, fat and protein metabolism
5) Vitamin B12 can promote methyl transferase
6) Vitamin B12 can Promote the development and maturation of red blood cells, so that the body hematopoietic function in a normal state, the prevention of pernicious anemia; maintain a healthy nervous system7) Vitamin B12 has the function of activate amino acids and promote the biosynthesis of nucleic acids, can promote protein synthesis,it plays an important role for growth and development of infants and young children
8) Vitamin B12 can metabolize fatty acids and make fat, carbohydrates, protein can be properly used by body.9) Vitamin B12 can eliminate irritability and help to keep concentration, enhance memory and sense of balanc10)Vitamin B12 is a indispensable vitamins to keep nervous system function completed and participate in developing a kind of lipoprotein in nerve tissue.
[In Medcine Field]
1) Vitamin B12 deficiency can lead to anemia and neurological disorders.
Can be used in infant food, usage of 10 ~ 30 mu g/kg;
In strengthening pinocytosis usage is 2 ~ 6 mu g/kg.
2).Vitamin B12 can treat nutritional and pregnancy anemia.
3) Vitamin B12 can treat nerve pain, muscle pain, joint pain.
4)Itamin B12 can treat uncontrolled hemorrhagic anemia, neuralgia and obstructive diseases.
[In Food Field]
Vitamin b17 can be used as food coloring agents in ham, sausage, ice cream, fish sauce and so on.
[In Feed Field]
As feed nutrition fortifier, have the function of the anemia, anemia of pernicious anemia, nutritional anemia, parasites are effective dosage of 15 to 30 mg/t
[In Cosmetic Field]
Vitamin B12 is generally known as hematopoietic vitamin, with excellent effect of skin regeneration, cell regeneration and blood generation it is an important component of the promotion of human metabolism. It can solve some skin problems as follows:
1)Skin tired, dull, dry skin and other issues;
2) Significantly dilute the appearance of fine lines and wrinkles arising due to increasing age;
3)After the repair sun, autumn and winter cold, dry skin caused by swelling, peeling, pain;
4)Pock marks, mosquito bite scars, burns burn scars;
5)After use cosmetic surgery to avoid scarring.
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Package
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1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
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Transit
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Fedex, TNT,DHL,EMS,and so on.
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Shipping port
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Shanghai/Tianjin/Dalian/Beijing/Xi'an
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Lead Time
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1-2 working days upon received the payment
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For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
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Hefei JOYE Import & Export CO.,LTD is a import and export trade company established in 2011.Approved by the Chinese government set up trade enterprises.The Customs Registration code of the company is 3401961603.
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