| CAS No.: | 103577-45-3 |
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| Formula: | C16h14f3n3o2s |
| EINECS: | / |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Audited Supplier Lansoprazole is in a class of drugs called proton pump inhibitors (PPI) which prevent the stomach from producing gastric acid.Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome that are caused by stomach acid. Lansoprazole, like other proton-pump inhibitors, blocks the enzyme in the
wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal.
Lansoprazole is a proton pump inhibitor (PPI) similar to omeprazole that inactivates the hydrogen/potassium-stimulated ATPase pumps in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. It is a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. Lansoprazole is a racemic mixture of (R)- and (S)-isomers. Dexlansoprazole is an isomer of lansoprazole that has a similar spectrum of activity and toxicities. Lansoprazole therapy is associated with a low rate of transient and asymptomatic serum aminotransferase elevations and is a reported, but very rare cause of clinically apparent liver injury.
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Test Item |
Analysis Specification |
Result |
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Description |
White to off white crystalline powder |
Conforms |
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Melting range |
129°C~132°C |
130.8°C-131°C |
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Loss on drying |
≤0.5% |
0.20 % |
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Specific rotation |
-58°~-62°(C=1,in CH3OH) |
-61.05° |
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Sulphated ash |
≤0.1% |
0.08 % |
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Heavy metals |
≤10ppm |
Conforms |
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Chlorides |
≤0.02% |
Conforms |
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Sulfates |
≤0.02% |
Conforms |
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Related substances (HPLC) |
Single impurity ≤0.2% Total impurities ≤0.5% |
0.05% 0.08% |
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Assay |
≥99.5% |
99.92% |
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Conclusion |
Accordance with the reference |
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1. Treatment of ulcers of the stomach and duodenum, and NSAID-induced ulcers.
2. Adjunctive treatment of Helicobacter pylori infection, alongside antibiotics. Treatment to kill Helicobacter pylori (H. pylori) causing ulcers or other problems involves using two other drugs besides lansoprazole. This treatment is known as "triple therapy", and involves taking twice daily for 10 or 14 days lansoprazole 30 mg, amoxicillin 1,000 mg, and clarithromycin 500 mg.
3. Treatment of gastroesophageal reflux disease (GERD) (also known as acid reflux disease).
4. Treatment of Zollinger-Ellison Syndrome.
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Packing
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1kg/bag ,25kg/bag;25kg/drum; according to your requirements
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Transit
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Fedex, TNT,DHL,EMS,and so on.
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Port
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Shanghai/Tianjin/Dalian/Beijing/Xi'an
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Lead Time
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3-5 working days upon received the payment
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| For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
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