Oral Medicine Grade Hydroxypropyl-Beta-Cyclodextrin CAS 128446-35-5

• CAS No.: 128446-35-5
• Formula: C63h112o42
• EINECS: 420-920-1
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: Oral Medicine Grade
• Colour: White
• Product Name: Beta-Cyclodextrin 2-Hydroxypropyl Ethers
• Storage: Cool Dry Place
• Sample: 10-20g
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: 99%
• Trademark: JULY
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

Product Description

Product Name	Oral Medicine grade Hydroxypropyl-beta-cyclodextrin
CAS No.	94035-02-6 128446-35-5 136019-12-0
Appearance	White Powder
Purity	98.0% --101.0%
MF	C105H196O56
Molecular weight	2354.64614
Quality standard	USP43-NF38
Grade	Oral Medicine grade
Other Grade	Cosmetic grade, technical grade, Injection grade

 

 

Oral medical grade hydroxypropyl beta cyclodextrin detection standard
Inspection items	CP2015	USP43-NF38
character	This product is white or nearly white amorphous or crystalline powder; odorless, slightly sweet; strong moisture absorption. Very soluble in water, soluble in ethanol.	This product is white or nearly white amorphous or crystalline powder; soluble in water .
Molar substitution degree	N/A	0.4-1.5
PH value	PH5.0-7.5	N/A
Clarity and color of solution	It should be clear and colorless	1.0g/2ml aqueous solution is clear and transparent
Water content	≤6.0%	≤10.0%
Chloride	≤0.05%	N/A
Beta cyclodextrin	≤0.5%	≤1.5%
1.2-propanediol	≤0.5%	≤2.5%
Residue on ignition	N/A	≤1.0%
Heavy metal	≤0.001%	N/A
Hydroxypropyloxy content	19.6%~26.3%	N/A
Total aerobic bacteria (CFU / g)	N/A	≤1000cfu/g
Total number of mould and yeast (CFU / g)	N/A	≤100 cfu/g
Bacterial endotoxin (EU / g)	N/A	According to the needs of the preparation

[Oral Medicine grade hydroxypropyl beta cyclodextrin] product performance:

The introduction of hydroxypropyl group breaks the intramolecular hydrogen bond of beta cyclodextrin and overcomes the main disadvantage of poor water solubility of betahcd while maintaining the cavity of cyclodextrin. Hydroxypropyl beta cyclodextrin is an ideal solubilizer and excipient for injection.

In the field of medicine, its main functions are as follows:

1. Solubilization and solubilization, make insoluble drugs dissolve, improve the solubility of active components of oily drugs, target drug delivery and protect the effectiveness of drug ingredients.

2. Improve the bioavailability of the drug, increase the curative effect of the drug or reduce the dosage.

3. Adjust or control the release rate of drugs to reduce the side effects.

4. Cover up the bad smell.

[Oral Medicine grade hydroxypropyl beta cyclodextrin] scope of application:

Hydroxypropyl beta cyclodextrin can be used in oral medicine, injection, mucosal drug delivery system (including nasal mucosa, rectum, cornea, etc.), transdermal absorption drug delivery system, lipophilic targeting drug carrier, and can also be used as protein protective agent and stabilizer.

Packaging and storage

Packaging: in line with drug packaging

Package specification: 1kg / bag, 2kg / bag, 10kg / bag / barrel

Storage: room temperature, dark

 

 

 

Application

 

1. In the field of food and spices

It can improve the stability and long-term of nutritional molecules, cover up or correct the bad smell and taste of food nutrients, and improve the production process and product quality. The solubility of the product in water is very good. The degree of substitution 4 or above can be mixed with water in any proportion, and can also be dissolved in 50% ethanol.

2. In cosmetics raw materials

As stabilizer, emulsifier and deodorizer, it can reduce the irritation of organic molecules in cosmetics to skin mucosa tissue, enhance the stability of effective ingredients, and prevent the volatilization and oxidation of nutrients. It has a certain relative hygroscopicity.

3. In the pharmaceutical industry

It is an ideal solubilizer and excipient for injection because of its low relative surface activity and hemolytic activity and no stimulation to muscle. It can improve the water solubility of insoluble drugs, increase the stability of drugs, improve the bioavailability of drugs, increase the curative effect of drugs or reduce the dosage. It can adjust or control the release rate of drugs and reduce the side effects of drugs. It can be used for oral drug, injection, mucosal drug delivery system (including nasal mucosa, rectum, cornea, etc.), transdermal absorption drug delivery system, lipophilic targeting drug carrier, and can also be used as protein protectant and stabilizer.

 

Packaging & Shipping

Packing	1kg/bag ,25kg/bag;25kg/drum; according to your requirements
Transit	Fedex, TNT,DHL,EMS,and so on.
Port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	3-5 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

Company Profile

Hefei Joye import export Co.,ltd is trading system gradually mature stable, scale, expanding opening flexible, the godfather management, Its marketing network, good business reputation has been praised by customers. The company has already established marketing channels with many manufactures and customers all over the world.

We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!

FAQ

 

1. What's the MOQ?
Usually1kg. It is based on the different product. Some are lg and some are 1 ton. Please be free to consult our salesman.
2. What's the shipping time?
If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
3. If I need less than the MOQ, is it possible?
 Yes. Please be free to consult our salesman.
4. Can you supply the free sample?
Usually it is possible. but the shipping cost be paid bycustomers. It based on the differentproduct.Please be free to consult our salesman.
5. How to store the product?
 Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
6. What's your main payment method?
T/T, trade assurance, west union, money gram.
7: Do you have COA, MSDS, co, Health certificate, form 9 or other certificate?
 Yes, we have. pls be free to contact us to get updated one.