Antidepressant Agent Bupropion HCl Powder/Bupropion Hydrochloride CAS 31677-93-7

• CAS No.: 31677-93-7
• Formula: C13h19cl2no
• EINECS: 250-759-9
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: USP BP EP
• Colour: Yellow
• Product Name: Bupropion Hydrochloride
• Grade: Medicine Grade
• Certificate: ISO9001/Halal/Kosher/GMP
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: Top grade
• Trademark: JULY
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

Product Description

 

Bupropion  Hydrochloride is an antidepressant that affects the chemicals in the brain that send information to each other. These chemical messengers are called neurotransmitters. Many experts believe that depression is caused by an imbalance in the amount of neurotransmitters released. The neurotransmitter that the nerve can circulate during a process called reuptake.  The role of bupropion is to inhibit the reuptake of dopamine, serotonin and norepinephrine; the behavior that causes more dopamine, serotonin and norepinephrine to transmit information to other nerves.

Product name	Bupropion Hydrochloride				Batch no		20200404
Manufacture date	Apr.05.2020		Retest Dat	Apr.04,2023	Report date			Apr.15,2020
Batch size	126.27kg				Standard			USP31
Test results
Items	Specifications					Results
Appearance	White powder					White powder
Solubility	Soluble in water,ethanol and 0.1Nhydrochloric acid					Conforms
Identification	IR absoption:Matches with standard					Conforms
	HPLC RT:Matches with standard					Conforms
	A solution of 1mg/ml in water meets the requirement of the  precipitate test for chloride					Conforms
Related compounds	TLC	m-chlorobenzoic acid:NMT0.2%				0.15%
		Any other individual impurity:NMT0.1%				None detected
	HPLC	Impurity-A:NMT0.2%				0.05%
		Impurity-B:NMT0.2%				None detected
		2-(tert-butylamino) bydrochloride:NMT 0.5%				None detected
		1-(3-chlorophenyl)-1,2-propanedione:NMT0.2%				None detected
		2-(tert-butylamino)-2-chloropropionphenone hydrochloride:NMT0.1%				None detected
		3'-Chloro:NMT0.1%				None detected
		2-bromo-3'-chloro:NMT0.1%				None detected
		2-(tert-butylamino)-3',4'-chloro hydrochloride:NMT0.2%				None detected
		2-(tert-butylamino)-3',5'-chloro hydrochloride:NMT0.2%				None detected
		Any other individual impurity:NMT0.1%				0.03%
		Total unidentified impurities:NMT0.3%				0.04%
	Total impurities:NMT1.0%					0.24%
Residual solvents(GC)	NMT300ppm					135ppm
	NMT3000ppm					270ppm
Water(KF)	NMT0.5%					0.08%
Assay(HPLC)	NLT98.0%and NMT102.0%(on anhydrous basis)					99.5%
Packaging	Preserve in well-closed,light-resistant containers
Conclusion	The product complies with the specification of USP31 standard.

Function

1.Bupropion hydrochloride is a unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.

2.Bupropion Hydrochloride is the hydrochloride salt of an aminoketone antidepressant. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.

Packaging & Shipping

Packing	1kg/bag ,25kg/bag;25kg/drum; according to your requirements
Transit	Fedex, TNT,DHL,EMS,and so on.
Port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	3-5 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

Company Profile

Hefei Joye import export Co.,ltd is trading system gradually mature stable, scale, expanding opening flexible, the godfather management, Its marketing network, good business reputation has been praised by customers. The company has already established marketing channels with many manufactures and customers all over the world.

We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!

FAQ

 

1. What's the MOQ?
Usually1kg. It is based on the different product. Some are lg and some are 1 ton. Please be free to consult our salesman.
2. What's the shipping time?
If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
3. If I need less than the MOQ, is it possible?
 Yes. Please be free to consult our salesman.
4. Can you supply the free sample?
Usually it is possible. but the shipping cost be paid bycustomers. It based on the differentproduct.Please be free to consult our salesman.
5. How to store the product?
 Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
6. What's your main payment method?
T/T, trade assurance, west union, money gram.
7: Do you have COA, MSDS, co, Health certificate, form 9 or other certificate?
 Yes, we have. pls be free to contact us to get updated one.