Cycloastragalol 99% Powder Astragalus Herbal Extract Raw Material CAS 84605-18-5

• State: Powder
• Character: Brown Powder
• Package: 1kg/Aluminum Foil Bag
• Test: HPLC
• Name: Cycloastragalol
• Source: Astragalus Extract
• Model NO.: Astragalus Extract
• CAS: 84605-18-5
• Transport Package: Drum/Tin
• Specification: 10-98%
• Trademark: NO
• Origin: China

Product Description

Cycloastragalol 99% Powder Astragalus Herbal Extract Raw Material CAS 84605-18-5

Detailed Photos

Product Description

Astragalus extract Astragalus P.E [Product source] This product is the dried root extract of legume Astragalus membranaceus (Fisch.) Bge. Dry astragalus root raw materials, wash, dry, crush, 10 times the amount of water, heat and boil for extraction three times, 2 hours each time, combine the three extracts, concentrate and evaporate the water to an extract with a specific gravity of d=1.20, leave it to cool, and extract the extract Add ethanol and stir, stand for precipitation, centrifuge the precipitate, continue to add ethanol to the precipitate, stir, stand and centrifuge to obtain crude astragalus polysaccharides, remove proteins and mucous components with a mixed solvent to obtain pure astragalus polysaccharides.
It has the functions of enhancing immunity, enhancing energy, anti-fatigue, anti-mutation, protecting liver, and inhibiting osteoclasts. Astragalus polysaccharides have the effect of lowering blood lipids, that is, lowering cholesterol and triglycerides, and raising high-density lipoproteins; it can prevent and treat cardiovascular and cerebrovascular diseases, such as atherosclerosis, coronary artery disease, peripheral vascular disease, and hyperlipidemia Wait. Astragaloside IV has the effect of significantly lowering blood sugar, glycosylated hemoglobin and urine protein, and can reduce AGEs in renal cortex and serum. It shows that Astragaloside IV has an antioxidant effect, and has an inhibitory effect on aldose reductase, and it also inhibits mesangium. The effect of cell proliferation and reducing kidney hypertrophy. Adding appropriate excipients to astragaloside IV can be made into oral preparations, which are used to prevent and treat diabetic nephropathy.

Product Name:	Astragalus extract
Active ingredients:	Astragaloside IV, Astragalus Polysaccharide
Appearance:	Brownish yellow or off-white powder
Shelf Life:	2 Years

 

Functions

 

1. Effects on blood vessels and blood pressure
Astragalus has the effect of expanding blood vessels and expanding coronary arteries. Therefore, it is believed that its antihypertensive effect is the result of direct expansion of peripheral blood vessels, and has no relationship with the heart, and has no relationship with the release of histamine or the effect of adrenergic receptors. It shows that the effect of Astragalus on blood pressure is related to the central neuropeptide, renin-angiotensin-aldosterone system, carnosine releasing enzyme-carnosine system, and hydroxyproline. The antihypertensive component of Astragalus was once considered to be an alkaline substance, but later it was discovered that the roots of Astragalus plants contain aminobutyric acid, and its content is almost parallel to the antihypertensive effect, so it is considered to be an effective component for antihypertensive. In terms of vascular effects, GABA does not completely represent astragalus. Astragalus can promote the migration and proliferation of vascular endothelial cells to varying degrees, which is beneficial to the process of angiogenesis. Astragalus membranaceus saponins II, III, IV and other saponins and formononetin, verbasin and other isoflavone compounds in Astragalus membranaceus can significantly improve the deformability of hatching red blood cells, which may be important for Astragalus membranaceus to improve hemorheological indicators. Mechanism, an important part of the effect of Astragalus on human erythrocyte membrane may be to protect human erythrocyte membrane from the attack of free radicals.
 2. Anti-fatigue effect
Astragalus polysaccharide 250mg/kg, 500mg/kg intraperitoneal injection, on normal mice and hydrocortisone-induced "Yang Deficiency" mice, swimming time at room temperature have a significant effect on swimming time, and increase the weight of the adrenal glands of mice under stress. Astragalus extract can significantly increase the plasma cortisol content, adrenal gland weight and lipid vacuole content in adrenal cortex cells in rats under swimming stress. Cerebral hypoxia caused by ligation of the carotid arteries on both sides has a significant antagonistic effect, which can significantly prolong the survival time of mice.
3. Long-term use of anti-aging effect
Astragalus has certain significance for preventing senile arteriosclerosis and improving senile lung function. In vitro cultured human embryonic lung diploid fibroblasts survived to 52 generations, while the cultured cells containing 0.2% astragalus extract survived to 77 generations. The changes in organelles during the aging process of the drug group and the aging ratio of the control group cells Basically the same, but the degree of change is light, and the rate of change is relatively slow, especially the Golgi complex of the cells in the drug group is particularly developed. Although the cells are senescent, they are not very senescent. Studies have proved that Astragalus has a good effect on prolonging life. As an anti-aging and prolonging drug, it is worthy of great attention and development.
4. Effects on the urinary system
Intravenous injection of astragalus injection can significantly increase the serum albumin of the rat minimally changed nephropathy model, significantly reduce the serum cholesterol, and increase the blood flow of the glomerular capillary filaments, and it also has a significant reduction in scrotal edema and ascites. The diet and mental state of the animals in the administration group are also better than those of the control group; Astragalus can significantly reduce the amount of protein in the urine; Pathological observations have also proved that the astragalus group has less disease, and this inhibitory effect on nephritis may be related to the enhanced metabolism of Astragalus. It is related to improving the nutritional status of the whole body. Astragalus can alleviate kidney disease in spontaneous lupus mice through immunomodulatory effects.
5. Hepatoprotective effect
Astragalus can protect the liver and prevent the reduction of liver glycogen. Two kinds of astragaloside ASI and SK can resist liver damage caused by D-galactosamine and acetaminophen. Astragaloside is an effective component of astragalus against hepatotoxic damage. Its mechanism is not only anti-biooxidation, but also related to metabolic regulation. Another study believes that Astragalus has a certain effect on preventing liver fibrosis.
6.Antibacterial, antiviral, and antitumor effects
Astragalus polysaccharides have obvious antagonistic effects on tuberculosis infection; other ingredients such as amino acids, alkaloids, flavonoids, etc. have been found to have significant anti-follicular stomatitis virus effects. Animal and transmutation cell experiments show that Astragalus injection has a certain blocking effect on the infection process of epidemic hemorrhagic fever and virus (EHFV) in suckling mice. Astragalus against Shigella Shigella, Bacillus anthracis, Alpha-Activated Streptococcus, Streptococcus sanguis, Diphtheria, Pseudodiphtheria, Pneumococcus, Staphylococcus aureus, Staphylococcus citrus, Staphylococcus albicans, Bacillus subtilis, etc. Has antibacterial effect.
 

Application

1.Applied in health product field; 
 

2.Applied in pharmaceutical field;
 

3.Applied in cosmetic field.
 

4.Applied in Food field.
 

Packaging & Shipping

Package	1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
Transit	Fedex, TNT,DHL,EMS,and so on.
Shipping port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	1-2 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

 

Our Advantages

Service:

1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.

Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service: 
1)International Authorized Third-Party Test For The Products You Demand. 
2)60 Days Warranty of quality of goods.

Company Profile

Hefei JOYE Import & Export CO.,LTD is a import and export trade company established in 2011.Approved by the Chinese government set up trade enterprises.The Customs Registration code of the company is 3401961603.

We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!

We adhering to the "pragmatic, serious, responsible, efficient" management thought construction of the unique enterprise culture, and provide the best service and high quality products, and you achieve mutual reciprocity and mutual benefit relations of cooperation.

 

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