High Quality Pure Fasudil HCl CAS 105628-07-7 Fasudil HCl, Free Sample

• CAS No.: 105628-07-7
• Formula: C14h18cln3o2s
• EINECS: N/a
• Variety: Cardiovascular Agents
• Feature: Stocked
• Usage: Organic Chemical Material
• Status: Solid State
• Appearance: White Crystalline Powder, White Powder
• Certificate: ISO9001/Halal/Kosher/GMP
• Test Method: HPLC
• Storage: Cool Dry Place
• Application: Medicine Grade
• Shipment: FedEx, DHL, TNT, EMS
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: 99%min
• Trademark: JOYE
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

High quality pure fasudil hcl cas 105628-07-7 fasudil hcl 

Product Name	High quality pure fasudil hcl cas 105628-07-7 fasudil hcl
CAS No.	105628-07-7
Appearance	white powder
Molecular formula	C14H18ClN3O2S
Certificate	ISO 9001
Free sample	10-20g
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life	24 Months

 

 
 

What is fasudil hcl ?

 

Fasudil hydrochloride is a cell-permeable, selective ROCK inhibitor which induces neuroprotection in vitro. Studies suggest that
when acting as a ROCK inhibitor, Fasudil reduces neutrophil transendothelial migration by diminishing cytoskeletal rearrangement
of endothelial cells. In addition, Fasudil significantly protects against MeHg-induced axonal degeneration and apoptotic cell
death in cultured cortical neurons. Alternate studies show that Fasudil plays an important role in osteoblastic differentiation of stromal cells via increasing the mRNA expression of collagen-I, osteocalcin, and bone morphogenetic protein-2 (BMP-2). Furthermore, noggin, a BMP-2 antagonist can reverse the effects of Fasudil induced mRNA expression of collagen-I and osteocalcin. Upon inhibition of Rho-kinase, Fasudil significantly stimulates FGF-2-induced accumulation of vascular endothelial growth factor (VEGF). Fasudil, Monohydrochloride Salt is an inhibitor of cGKI, MSK1, PKA, PRK2, Rock-2, AMPK, CaMKII, Polycystin-1 and Rsk-1.

Fasudil Hydrochloride is a new with a wide range of pharmacological effects, developed by Asahi Kasei Corporation (Japan.) It is a cardiovascular and cerebrovascular which improves symptoms of ischemic cerebrovascular disease such as cerebral vasospasm following subarachnoid hemorrhage. It has significant neuroprotective and therapeutic effects for ischemic cerebrovascular disease, and is suited for clinical use, particularly at the grassroots level to reduce mortality and improve quality of life. 

Packing :	1kg/bag ,25kg/bag;25kg/drum; according to your requirements
Transit:	Fedex, TNT,DHL,EMS,and so on.
Port:	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time :	3-5 working days upon received the payment
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

Hefei Joye Import Export Co., Ltd. is a new import and export trade company established in 2011. The Customs Registration Code of our company is 3401961603. Our company's trading system becomes mature and stable. Our company has already established marketing channels. We have customers all over the world. We have also expanded our business scale. Our products: 1) Chemical raw materials: pharmaceutical intermediates, plant extracts, food additives & spices. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. 2) Building materials: steel, flooring, fence, glass and so on 3) Hardware: screws and bearings, architectural hardware, chains, locks and so on Our products are affordable. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success! We adhere to the tenet of "Pragmatic, Serious, Responsible, Efficient". We provide the best services and high quality products